The Integrative Movement Sciences Institute (IMSI) is an NSF Biology Integration Institute dedicated to advancing understanding of muscular control of movement across organizational scales from molecular to organismal and ecological. CIMS serves as the UCI-based hub and administrative center of IMSI, which connects a network of faculty affiliates from over 20 institutions. IMSI aims to transform understanding of movement sciences through collaborative, interdisciplinary research and training across multiple scientific disciplines.
This network unites experts in biomechanics, biophysics, physiology, neuroscience, and engineering, all committed to investigating the principles behind agile, efficient, and adaptive movement. Together, NSF-IMSI Affiliates work collaboratively to uncover the complex biological and mechanical processes that drive movement, from molecular to whole-organism scales, inspiring discoveries with far-reaching implications for health, rehabilitation, and technological innovation. The institute also provides inclusive training for the next generation of scientists, emphasizing near-peer mentorship, team science, leadership development, and open-data sharing, to equip a diverse population of trainees with the skills needed for interdisciplinary research. Although IMSI is a year-round program, one of the highlights of IMSI's program is the Summer Institute.
Co-Principal Investigators
Monica Daley
Dr. Daley works at the interface of biomechanics, neuromuscular physiology and neuroscience, to understand how humans and animals achieve integrated function for stable and agile movement, particularly in non-steady locomotor tasks. These studies aim to reveal general principles of movement that inform human and animal health and welfare— including clinical gait assessment, treatment of movement disorders, rehabilitation strategies, and bio-inspired engineering of legged robots and mobility assistance technology.
Kiisa Nishikawa
The Nishikawa laboratory collaborates widely with scientists and engineers to investigate the biomechanics and biophysics of muscles from molecules to movement, with an emphasis on investigating the role of titin in muscle force production. The laboratory’s current focus is linking in vivo experimental data to ex vivo models and experiments. This work has led to many new and exciting ideas, including the idea that muscle is a tunable material, and the related idea that neural control permits, rather than instructs, muscle force. Currently, they have experiments and modeling projects ranging from skinned fiber and intact muscle physiology to biomechanics, kinesiology and exercise science.
IMSI Research Network Affiliates
James Finley
University of Southern California
Division of Biokinesiology and Physical Therapy
Alena Grabowski
University of Colorado Boulder
Claire Trevor School of the Arts
Natalie Holt
University of California, Riverside
Evolution, Ecology, and Organismal Biology
Jill McNitt-Gray
University of Southern California
Dornsife College of Letters, Arts, And Sciences
David Reinkensmeyer
University of California, Irvine
The Henry Samueli School of Engineering
Gregory Sawicki
Georgia Tech
The George W. Woodruff School of Mechanical Engineering
Nidhi Seethapathi
University of Pennsylvania
Bioengineering and Neuroscience
Bert Tanner
Washington State University
Department of Molecular Biosciences
Madhusudhan Venkadesan
Yale University
School of Engineering & Applied Science
Sasha Voloshina
University of California, Irvine
The Henry Samueli School of Engineering